The use of supplementary immunisation activities to improve uptake of current and future vaccines in low-income and middle-income countries: a systematic review protocol

نویسندگان

  • Benjamin M Kagina
  • Charles S Wiysonge
  • Shingai Machingaidze
  • Leila H Abdullahi
  • Esther Adebayo
  • Olalekan A Uthman
  • Gregory D Hussey
چکیده

INTRODUCTION Immunisation coverage data in low-income and middle-income countries (LMICs) suggest that more strategies need to be implemented to achieve and sustain optimal vaccine uptake. Among possible strategies to improve immunisation coverage are supplementary immunisation activities (SIAs). We are therefore interested in conducting a systematic review to assess whether SIAs complement routine immunisation programmes to improve vaccination coverage and prevent disease outbreaks. METHODS Our systematic review will focus on studies conducted in LMICs. With the help of an information specialist, we will search for eligible studies in PubMed, Web of Science, Scopus, Africa-Wide, Cochrane Library, WHOLIS, CINAHL, PDQ-Evidence as well as reference lists of relevant publications. Additionally, we will contact relevant organisations such as WHO and GAVI. Two authors will independently extract data from eligible studies and independently assess risk of bias by assessing the adequacy of study characteristics. The primary meta-analysis will use random effects models due to expected interstudies heterogeneity. Dichotomous data will be analysed using relative risk and continuous data using weighted mean differences (or standardised mean differences), both with 95% CIs. DISCUSSION The findings from this systematic review will be discussed in the context of strengthening routine childhood immunisation services, routine adolescent immunisation services and introduction of future vaccines against tuberculosis and HIV/AIDS. STUDY STRENGTHS Unbiased selection of many studies conducted in different settings. This will strengthen the validity of the review results. STUDY LIMITATIONS Heterogeneity of the study settings of the low-income, lower-middle-income and upper-middle-income countries as well as heterogeneity in study designs.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Realist Synthesis of the International Theory and Evidence on Strategies to Improve Childhood Vaccination in Low- and Middle-Income Countries: Developing Strategies for the Nigerian Healthcare System

Background Childhood vaccination coverage rates in low- and middle-income countries (LMICs) vary significantly, with some countries achieving higher rates than others. Several attempts have been made in Nigeria to achieve universal vaccination coverage but with limited success. This study aimed to analyse strategies used to improve ...

متن کامل

The Implications of Global Neurosurgery for Low- and Middle-Income Countries. The Case of Cameroon.

The unequal distribution of neurosurgical resources and diseases in the world contributes to inequality. Eight in ten neurosurgical cases needing essential neurosurgical care are found in low- and middle-income countries (LMICs); however, LMICs lack the neurosurgical resources to address these needs. Besides, where neurosurgical care is available, it is not financially accessible to the majorit...

متن کامل

Coliforms Contamination and Hygienic Status of Milk Chain in Emerging Economies

Emerging economies have often poor hygiene practices in traditional milk and dairy production all over the world. Therefore, pathogenic bacteria in milk pose major public health concerns especially for those communities who still consume raw milk. Escherichia coli and coliforms are often used as indicator microorganisms, so their presence in food implies poor hygiene and sanitary practices. The...

متن کامل

Initiatives in Medical Volunteerism Aimed at Reducing the Burden of Orthopedic Disease in Low- and Middle-Income Countries

While infectious disease garners much attention and research funding globally, initiatives aimed at treating traumatic orthopedic injuries are underfunded despite such injuries accounting for a significant degree of morbidity worldwide. In recent years, a number of organizations have sought to alleviate this burden through treatment and educational initiatives in low- and middle-income countrie...

متن کامل

The Impact of Conflict on Immunisation Coverage in 16 Countries

Background Military conflict has been an ongoing determinant of inequitable immunisation coverage in many low- and middle-income countries, yet the impact of conflict on the attainment of global health goals has not been fully addressed. This review will describe and analyse the association between conflict, immunisation coverage and vaccine-preventable disease (VPD) outbreaks, along with...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:

دوره 4  شماره 

صفحات  -

تاریخ انتشار 2014